WARHEAD COMMAND CENTER: d6706e03 · DYRK1A

CUE

8yev (CHAIN B)

65.0% EXPOSED

SASA atoms

13 / 20

% buried

35.0%

SASA

75.5Å²

9OL

6a1g (CHAIN B)

64.0% EXPOSED

SASA atoms

16 / 25

% buried

36.0%

SASA

132.7Å²

B7W

6ej4 (CHAIN C)

63.6% EXPOSED

SASA atoms

14 / 22

% buried

36.4%

SASA

98.8Å²

B6Q

6eiv (CHAIN C)

57.6% EXPOSED

SASA atoms

19 / 33

% buried

42.4%

SASA

150.8Å²

B5Z

6eij (CHAIN B)

57.6% EXPOSED

SASA atoms

19 / 33

% buried

42.4%

SASA

210.1Å²

B6Z

6eiq (CHAIN C)

56.7% EXPOSED

SASA atoms

17 / 30

% buried

43.3%

SASA

164.3Å²

3NG

7z5n (CHAIN E)

56.0% EXPOSED

SASA atoms

14 / 25

% buried

44.0%

SASA

101.7Å²

3NG

7z5n (CHAIN C)

56.0% EXPOSED

SASA atoms

14 / 25

% buried

44.0%

SASA

109.1Å²

B5T

6eif (CHAIN D)

56.0% EXPOSED

SASA atoms

14 / 25

% buried

44.0%

SASA

137.1Å²

3NG

7z5n (CHAIN D)

56.0% EXPOSED

SASA atoms

14 / 25

% buried

44.0%

SASA

82.8Å²

9OL

6a1g (CHAIN A)

56.0% EXPOSED

SASA atoms

14 / 25

% buried

44.0%

SASA

119.1Å²

3NG

7z5n (CHAIN B)

56.0% EXPOSED

SASA atoms

14 / 25

% buried

44.0%

SASA

88.8Å²

B5Z

6eij (CHAIN D)

54.5% EXPOSED

SASA atoms

18 / 33

% buried

45.5%

SASA

196.2Å²

QY8

7a4r (CHAIN A)

54.5% EXPOSED

SASA atoms

6 / 11

% buried

45.5%

SASA

57.9Å²

B6H

6eir (CHAIN B)

54.3% EXPOSED

SASA atoms

19 / 35

% buried

45.7%

SASA

229.5Å²

39I

7oy6 (CHAIN C)

53.8% EXPOSED

SASA atoms

14 / 26

% buried

46.2%

SASA

114.6Å²

D15

2wo6 (CHAIN B)

53.1% EXPOSED

SASA atoms

17 / 32

% buried

46.9%

SASA

145.4Å²

D15

2vx3 (CHAIN B)

53.1% EXPOSED

SASA atoms

17 / 32

% buried

46.9%

SASA

121.3Å²

9OF

6a1f (CHAIN A)

52.6% EXPOSED

SASA atoms

10 / 19

% buried

47.4%

SASA

71.8Å²

B5T

6eif (CHAIN C)

52.0% EXPOSED

SASA atoms

13 / 25

% buried

48.0%

SASA

139.1Å²

3NG

7z5n (CHAIN A)

52.0% EXPOSED

SASA atoms

13 / 25

% buried

48.0%

SASA

82.6Å²

3NG

7z5n (CHAIN F)

52.0% EXPOSED

SASA atoms

13 / 25

% buried

48.0%

SASA

80.2Å²

CC9

9fpx (CHAIN B)

51.9% EXPOSED

SASA atoms

14 / 27

% buried

48.1%

SASA

162.5Å²

B5Z

6eij (CHAIN C)

51.5% EXPOSED

SASA atoms

17 / 33

% buried

48.5%

SASA

174.0Å²

B6Q

6eiv (CHAIN A)

51.5% EXPOSED

SASA atoms

17 / 33

% buried

48.5%

SASA

166.6Å²

B5Z

6eij (CHAIN A)

51.5% EXPOSED

SASA atoms

17 / 33

% buried

48.5%

SASA

145.5Å²

B6H

6eir (CHAIN C)

51.4% EXPOSED

SASA atoms

18 / 35

% buried

48.6%

SASA

243.0Å²

AWR

5aik (CHAIN A)

50.0% EXPOSED

SASA atoms

12 / 24

% buried

50.0%

SASA

86.8Å²

B6Z

6eiq (CHAIN A)

50.0% EXPOSED

SASA atoms

15 / 30

% buried

50.0%

SASA

181.0Å²

B6Z

6eiq (CHAIN D)

50.0% EXPOSED

SASA atoms

15 / 30

% buried

50.0%

SASA

160.2Å²

CUE

8yev (CHAIN A)

50.0% EXPOSED

SASA atoms

10 / 20

% buried

50.0%

SASA

74.7Å²

D15

2vx3 (CHAIN A)

50.0% EXPOSED

SASA atoms

16 / 32

% buried

50.0%

SASA

130.4Å²

B7W

6ej4 (CHAIN A)

50.0% EXPOSED

SASA atoms

11 / 22

% buried

50.0%

SASA

101.5Å²

IWU

7zh8 (CHAIN C)

50.0% EXPOSED

SASA atoms

10 / 20

% buried

50.0%

SASA

115.8Å²

D15

2wo6 (CHAIN A)

50.0% EXPOSED

SASA atoms

16 / 32

% buried

50.0%

SASA

141.3Å²

D15

2vx3 (CHAIN D)

50.0% EXPOSED

SASA atoms

16 / 32

% buried

50.0%

SASA

118.6Å²

D15

2vx3 (CHAIN C)

50.0% EXPOSED

SASA atoms

16 / 32

% buried

50.0%

SASA

120.6Å²

2K2

4nct (CHAIN C)

48.8% EXPOSED

SASA atoms

21 / 43

% buried

51.2%

SASA

163.7Å²

2C3

4mq1 (CHAIN A)

48.6% EXPOSED

SASA atoms

18 / 37

% buried

51.4%

SASA

152.2Å²

6ZV

7o7k (CHAIN A)

48.6% EXPOSED

SASA atoms

18 / 37

% buried

51.4%

SASA

188.9Å²

B6H

6eir (CHAIN D)

48.6% EXPOSED

SASA atoms

17 / 35

% buried

51.4%

SASA

224.7Å²

B6Q

6eiv (CHAIN D)

48.5% EXPOSED

SASA atoms

16 / 33

% buried

51.5%

SASA

143.6Å²

XIR

8t2h (CHAIN A)

48.4% EXPOSED

SASA atoms

15 / 31

% buried

51.6%

SASA

132.6Å²

XIR

8t2h (CHAIN B)

48.4% EXPOSED

SASA atoms

15 / 31

% buried

51.6%

SASA

116.9Å²

CC9

9fpx (CHAIN A)

48.1% EXPOSED

SASA atoms

13 / 27

% buried

51.9%

SASA

130.0Å²

2C4

4mq2 (CHAIN A)

48.1% EXPOSED

SASA atoms

13 / 27

% buried

51.9%

SASA

113.4Å²

3NG

7z5n (CHAIN H)

48.0% EXPOSED

SASA atoms

12 / 25

% buried

52.0%

SASA

104.6Å²

3NG

7z5n (CHAIN G)

48.0% EXPOSED

SASA atoms

12 / 25

% buried

52.0%

SASA

58.7Å²

B5T

6eif (CHAIN B)

48.0% EXPOSED

SASA atoms

12 / 25

% buried

52.0%

SASA

122.5Å²

B6Z

6eiq (CHAIN B)

46.7% EXPOSED

SASA atoms

14 / 30

% buried

53.3%

SASA

177.5Å²

AJG

5a4t (CHAIN A)

46.7% EXPOSED

SASA atoms

7 / 15

% buried

53.3%

SASA

86.9Å²

2C3

4mq1 (CHAIN D)

45.9% EXPOSED

SASA atoms

17 / 37

% buried

54.1%

SASA

166.7Å²

2C3

4mq1 (CHAIN B)

45.9% EXPOSED

SASA atoms

17 / 37

% buried

54.1%

SASA

150.9Å²

B6B

6eil (CHAIN D)

45.8% EXPOSED

SASA atoms

11 / 24

% buried

54.2%

SASA

81.3Å²

4E2

4ylk (CHAIN A)

45.5% EXPOSED

SASA atoms

10 / 22

% buried

54.5%

SASA

87.7Å²

QY8

7a4r (CHAIN B)

45.5% EXPOSED

SASA atoms

5 / 11

% buried

54.5%

SASA

46.3Å²

QYE

7a4s (CHAIN A)

45.5% EXPOSED

SASA atoms

5 / 11

% buried

54.5%

SASA

60.6Å²

B6Q

6eiv (CHAIN B)

45.5% EXPOSED

SASA atoms

15 / 33

% buried

54.5%

SASA

147.7Å²

IWU

7zh8 (CHAIN A)

45.0% EXPOSED

SASA atoms

9 / 20

% buried

55.0%

SASA

106.6Å²

IWU

7zh8 (CHAIN D)

45.0% EXPOSED

SASA atoms

9 / 20

% buried

55.0%

SASA

104.9Å²

2C4

4mq2 (CHAIN C)

44.4% EXPOSED

SASA atoms

12 / 27

% buried

55.6%

SASA

103.9Å²

4VZ

7fhs (CHAIN C)

44.4% EXPOSED

SASA atoms

8 / 18

% buried

55.6%

SASA

74.7Å²

2C4

4mq2 (CHAIN B)

44.4% EXPOSED

SASA atoms

12 / 27

% buried

55.6%

SASA

118.5Å²

2K2

4nct (CHAIN D)

44.2% EXPOSED

SASA atoms

19 / 43

% buried

55.8%

SASA

199.5Å²

R7O

8c3r (CHAIN B)

44.1% EXPOSED

SASA atoms

15 / 34

% buried

55.9%

SASA

99.7Å²

MLW

6t6a (CHAIN A)

43.8% EXPOSED

SASA atoms

7 / 16

% buried

56.2%

SASA

34.8Å²

2C3

4mq1 (CHAIN C)

43.2% EXPOSED

SASA atoms

16 / 37

% buried

56.8%

SASA

166.3Å²

QIV

5a3x (CHAIN B)

42.9% EXPOSED

SASA atoms

6 / 14

% buried

57.1%

SASA

45.8Å²

B6H

6eir (CHAIN A)

42.9% EXPOSED

SASA atoms

15 / 35

% buried

57.1%

SASA

218.3Å²

ZC3

5a4l (CHAIN A)

42.9% EXPOSED

SASA atoms

6 / 14

% buried

57.1%

SASA

44.7Å²

QIV

5a3x (CHAIN D)

42.9% EXPOSED

SASA atoms

6 / 14

% buried

57.1%

SASA

36.4Å²

ZC3

5a4l (CHAIN D)

42.9% EXPOSED

SASA atoms

6 / 14

% buried

57.1%

SASA

50.9Å²

OPW

6yf8 (CHAIN B)

42.9% EXPOSED

SASA atoms

9 / 21

% buried

57.1%

SASA

89.0Å²

4E1

4ylj (CHAIN B)

42.9% EXPOSED

SASA atoms

9 / 21

% buried

57.1%

SASA

64.0Å²

KQE

6s11 (CHAIN B)

42.3% EXPOSED

SASA atoms

11 / 26

% buried

57.7%

SASA

69.9Å²

2K2

4nct (CHAIN A)

41.9% EXPOSED

SASA atoms

18 / 43

% buried

58.1%

SASA

170.6Å²

AWR

5aik (CHAIN C)

41.7% EXPOSED

SASA atoms

10 / 24

% buried

58.3%

SASA

84.8Å²

AWR

5aik (CHAIN D)

41.7% EXPOSED

SASA atoms

10 / 24

% buried

58.3%

SASA

61.0Å²

YOX

8r8e (CHAIN C)

41.2% EXPOSED

SASA atoms

7 / 17

% buried

58.8%

SASA

43.6Å²

B7W

6ej4 (CHAIN B)

40.9% EXPOSED

SASA atoms

9 / 22

% buried

59.1%

SASA

80.8Å²

B7W

6ej4 (CHAIN D)

40.9% EXPOSED

SASA atoms

9 / 22

% buried

59.1%

SASA

64.4Å²

2C4

4mq2 (CHAIN D)

40.7% EXPOSED

SASA atoms

11 / 27

% buried

59.3%

SASA

104.4Å²

6ZV

7o7k (CHAIN B)

40.5% EXPOSED

SASA atoms

15 / 37

% buried

59.5%

SASA

199.5Å²

AJG

5a4t (CHAIN D)

40.0% EXPOSED

SASA atoms

6 / 15

% buried

60.0%

SASA

91.7Å²

AJG

5a4t (CHAIN C)

40.0% EXPOSED

SASA atoms

6 / 15

% buried

60.0%

SASA

80.5Å²

AJG

5a4t (CHAIN B)

40.0% EXPOSED

SASA atoms

6 / 15

% buried

60.0%

SASA

69.6Å²

IWU

7zh8 (CHAIN B)

40.0% EXPOSED

SASA atoms

8 / 20

% buried

60.0%

SASA

106.3Å²

7QQ

5a4e (CHAIN A)

40.0% EXPOSED

SASA atoms

6 / 15

% buried

60.0%

SASA

45.1Å²

7QQ

5a4e (CHAIN B)

40.0% EXPOSED

SASA atoms

6 / 15

% buried

60.0%

SASA

41.2Å²

RKK

7ajv (CHAIN A)

40.0% EXPOSED

SASA atoms

10 / 25

% buried

60.0%

SASA

122.5Å²

JHW

6qu2 (CHAIN C)

39.1% EXPOSED

SASA atoms

9 / 23

% buried

60.9%

SASA

88.7Å²

4WD

7fht (CHAIN B)

38.9% EXPOSED

SASA atoms

7 / 18

% buried

61.1%

SASA

65.3Å²

MFR

7a5b (CHAIN B)

38.9% EXPOSED

SASA atoms

7 / 18

% buried

61.1%

SASA

36.1Å²

4VZ

7fhs (CHAIN D)

38.9% EXPOSED

SASA atoms

7 / 18

% buried

61.1%

SASA

70.9Å²

4VZ

7fhs (CHAIN B)

38.9% EXPOSED

SASA atoms

7 / 18

% buried

61.1%

SASA

67.0Å²

4WD

7fht (CHAIN C)

38.9% EXPOSED

SASA atoms

7 / 18

% buried

61.1%

SASA

66.4Å²

KQE

6s11 (CHAIN A)

38.5% EXPOSED

SASA atoms

10 / 26

% buried

61.5%

SASA

59.5Å²

OPW

6yf8 (CHAIN D)

38.1% EXPOSED

SASA atoms

8 / 21

% buried

61.9%

SASA

87.6Å²

4E1

4ylj (CHAIN A)

38.1% EXPOSED

SASA atoms

8 / 21

% buried

61.9%

SASA

60.0Å²

OPW

6yf8 (CHAIN C)

38.1% EXPOSED

SASA atoms

8 / 21

% buried

61.9%

SASA

77.5Å²

4E1

4ylj (CHAIN C)

38.1% EXPOSED

SASA atoms

8 / 21

% buried

61.9%

SASA

63.9Å²

OPW

6yf8 (CHAIN A)

38.1% EXPOSED

SASA atoms

8 / 21

% buried

61.9%

SASA

78.6Å²

HRM

3anr (CHAIN B)

37.5% EXPOSED

SASA atoms

6 / 16

% buried

62.5%

SASA

46.1Å²

B6B

6eil (CHAIN B)

37.5% EXPOSED

SASA atoms

9 / 24

% buried

62.5%

SASA

74.7Å²

Q8J

6uip (CHAIN C)

37.5% EXPOSED

SASA atoms

12 / 32

% buried

62.5%

SASA

121.8Å²

HRM

3anr (CHAIN D)

37.5% EXPOSED

SASA atoms

6 / 16

% buried

62.5%

SASA

37.8Å²

B6B

6eil (CHAIN A)

37.5% EXPOSED

SASA atoms

9 / 24

% buried

62.5%

SASA

81.3Å²

HRM

3anr (CHAIN A)

37.5% EXPOSED

SASA atoms

6 / 16

% buried

62.5%

SASA

41.2Å²

5PW

5a54 (CHAIN A)

37.5% EXPOSED

SASA atoms

6 / 16

% buried

62.5%

SASA

72.1Å²

QZW

7a5l (CHAIN A)

37.5% EXPOSED

SASA atoms

9 / 24

% buried

62.5%

SASA

70.3Å²

QYB

7a52 (CHAIN A)

37.5% EXPOSED

SASA atoms

6 / 16

% buried

62.5%

SASA

37.9Å²

QYB

7a52 (CHAIN B)

37.5% EXPOSED

SASA atoms

6 / 16

% buried

62.5%

SASA

44.9Å²

MLW

6t6a (CHAIN C)

37.5% EXPOSED

SASA atoms

6 / 16

% buried

62.5%

SASA

27.5Å²

Q8J

6uip (CHAIN B)

37.5% EXPOSED

SASA atoms

12 / 32

% buried

62.5%

SASA

127.6Å²

EHB

3anq (CHAIN A)

37.5% EXPOSED

SASA atoms

6 / 16

% buried

62.5%

SASA

45.6Å²

2K2

4nct (CHAIN B)

37.2% EXPOSED

SASA atoms

16 / 43

% buried

62.8%

SASA

174.3Å²

RHH

7ak2 (CHAIN B)

37.0% EXPOSED

SASA atoms

10 / 27

% buried

63.0%

SASA

46.3Å²

EKU

6ln1 (CHAIN A)

37.0% EXPOSED

SASA atoms

10 / 27

% buried

63.0%

SASA

51.9Å²

R05

7a5n (CHAIN B)

37.0% EXPOSED

SASA atoms

10 / 27

% buried

63.0%

SASA

74.3Å²

4E3

4yll (CHAIN A)

36.4% EXPOSED

SASA atoms

8 / 22

% buried

63.6%

SASA

88.2Å²

QIV

5a3x (CHAIN C)

35.7% EXPOSED

SASA atoms

5 / 14

% buried

64.3%

SASA

40.0Å²

Y3L

5a4q (CHAIN B)

35.7% EXPOSED

SASA atoms

5 / 14

% buried

64.3%

SASA

73.4Å²

Y3L

5a4q (CHAIN A)

35.7% EXPOSED

SASA atoms

5 / 14

% buried

64.3%

SASA

83.6Å²

QYK

7a51 (CHAIN A)

35.7% EXPOSED

SASA atoms

5 / 14

% buried

64.3%

SASA

50.2Å²

QZ2

7a55 (CHAIN A)

35.7% EXPOSED

SASA atoms

5 / 14

% buried

64.3%

SASA

27.1Å²

6SD

7a4z (CHAIN A)

35.7% EXPOSED

SASA atoms

5 / 14

% buried

64.3%

SASA

23.5Å²

RKZ

7ajy (CHAIN B)

35.7% EXPOSED

SASA atoms

10 / 28

% buried

64.3%

SASA

64.0Å²

ZC3

5a4l (CHAIN C)

35.7% EXPOSED

SASA atoms

5 / 14

% buried

64.3%

SASA

36.5Å²

QIV

5a3x (CHAIN A)

35.7% EXPOSED

SASA atoms

5 / 14

% buried

64.3%

SASA

39.2Å²

Y3L

5a4q (CHAIN D)

35.7% EXPOSED

SASA atoms

5 / 14

% buried

64.3%

SASA

60.6Å²

Y3L

5a4q (CHAIN C)

35.7% EXPOSED

SASA atoms

5 / 14

% buried

64.3%

SASA

61.9Å²

B7B

6eip (CHAIN B)

35.5% EXPOSED

SASA atoms

11 / 31

% buried

64.5%

SASA

95.9Å²

B7B

6eip (CHAIN C)

35.5% EXPOSED

SASA atoms

11 / 31

% buried

64.5%

SASA

128.3Å²

YOX

8r8e (CHAIN A)

35.3% EXPOSED

SASA atoms

6 / 17

% buried

64.7%

SASA

33.1Å²

YOX

8r8e (CHAIN B)

35.3% EXPOSED

SASA atoms

6 / 17

% buried

64.7%

SASA

44.7Å²

YOX

8r8e (CHAIN D)

35.3% EXPOSED

SASA atoms

6 / 17

% buried

64.7%

SASA

35.9Å²

3RA

4aze (CHAIN A)

34.8% EXPOSED

SASA atoms

8 / 23

% buried

65.2%

SASA

44.2Å²

KR8

6s1i (CHAIN D)

34.8% EXPOSED

SASA atoms

8 / 23

% buried

65.2%

SASA

40.9Å²

JHW

6qu2 (CHAIN A)

34.8% EXPOSED

SASA atoms

8 / 23

% buried

65.2%

SASA

77.6Å²

JHW

6qu2 (CHAIN D)

34.8% EXPOSED

SASA atoms

8 / 23

% buried

65.2%

SASA

76.7Å²

KR8

6s1i (CHAIN A)

34.8% EXPOSED

SASA atoms

8 / 23

% buried

65.2%

SASA

44.6Å²

QS0

8c3g (CHAIN A)

34.4% EXPOSED

SASA atoms

11 / 32

% buried

65.6%

SASA

164.1Å²

QS0

8c3g (CHAIN B)

34.4% EXPOSED

SASA atoms

11 / 32

% buried

65.6%

SASA

166.5Å²

QKG

6uwy (CHAIN D)

34.1% EXPOSED

SASA atoms

14 / 41

% buried

65.9%

SASA

61.4Å²

RJ5

7aj2 (CHAIN A)

33.3% EXPOSED

SASA atoms

5 / 15

% buried

66.7%

SASA

37.5Å²

4WD

7fht (CHAIN D)

33.3% EXPOSED

SASA atoms

6 / 18

% buried

66.7%

SASA

62.9Å²

7QQ

5a4e (CHAIN C)

33.3% EXPOSED

SASA atoms

5 / 15

% buried

66.7%

SASA

48.9Å²

AWR

5aik (CHAIN B)

33.3% EXPOSED

SASA atoms

8 / 24

% buried

66.7%

SASA

69.0Å²

R05

7a5n (CHAIN A)

33.3% EXPOSED

SASA atoms

9 / 27

% buried

66.7%

SASA

54.9Å²

RKH

7ajs (CHAIN B)

33.3% EXPOSED

SASA atoms

6 / 18

% buried

66.7%

SASA

36.8Å²

RJ2

7aja (CHAIN A)

33.3% EXPOSED

SASA atoms

7 / 21

% buried

66.7%

SASA

75.8Å²

4E1

4ylj (CHAIN D)

33.3% EXPOSED

SASA atoms

7 / 21

% buried

66.7%

SASA

50.1Å²

4VZ

7fhs (CHAIN A)

33.3% EXPOSED

SASA atoms

6 / 18

% buried

66.7%

SASA

69.8Å²

RKQ

7ajw (CHAIN A)

33.3% EXPOSED

SASA atoms

9 / 27

% buried

66.7%

SASA

59.6Å²

MFR

7a5b (CHAIN A)

33.3% EXPOSED

SASA atoms

6 / 18

% buried

66.7%

SASA

40.9Å²

R7O

8c3r (CHAIN A)

32.4% EXPOSED

SASA atoms

11 / 34

% buried

67.6%

SASA

98.2Å²

RJZ

7akb (CHAIN A)

32.1% EXPOSED

SASA atoms

9 / 28

% buried

67.9%

SASA

70.7Å²

RK2

7aka (CHAIN B)

32.1% EXPOSED

SASA atoms

9 / 28

% buried

67.9%

SASA

68.5Å²

RJZ

7akb (CHAIN B)

32.1% EXPOSED

SASA atoms

9 / 28

% buried

67.9%

SASA

48.9Å²

B5T

6eif (CHAIN A)

32.0% EXPOSED

SASA atoms

8 / 25

% buried

68.0%

SASA

102.2Å²

RKK

7ajv (CHAIN B)

32.0% EXPOSED

SASA atoms

8 / 25

% buried

68.0%

SASA

109.2Å²

RKW

7ajm (CHAIN B)

31.8% EXPOSED

SASA atoms

7 / 22

% buried

68.2%

SASA

79.1Å²

RKW

7ajm (CHAIN A)

31.8% EXPOSED

SASA atoms

7 / 22

% buried

68.2%

SASA

80.0Å²

4H5

4yu2 (CHAIN C)

31.6% EXPOSED

SASA atoms

6 / 19

% buried

68.4%

SASA

36.2Å²

EHB

3anq (CHAIN D)

31.2% EXPOSED

SASA atoms

5 / 16

% buried

68.8%

SASA

42.1Å²

EHB

3anq (CHAIN C)

31.2% EXPOSED

SASA atoms

5 / 16

% buried

68.8%

SASA

43.2Å²

HRM

3anr (CHAIN C)

31.2% EXPOSED

SASA atoms

5 / 16

% buried

68.8%

SASA

46.0Å²

QYH

7a4w (CHAIN A)

31.2% EXPOSED

SASA atoms

5 / 16

% buried

68.8%

SASA

31.6Å²

QYH

7a4w (CHAIN B)

31.2% EXPOSED

SASA atoms

5 / 16

% buried

68.8%

SASA

26.6Å²

Q8J

6uip (CHAIN A)

31.2% EXPOSED

SASA atoms

10 / 32

% buried

68.8%

SASA

137.8Å²

RJ8

7aj8 (CHAIN A)

31.2% EXPOSED

SASA atoms

5 / 16

% buried

68.8%

SASA

27.8Å²

5PW

5a54 (CHAIN C)

31.2% EXPOSED

SASA atoms

5 / 16

% buried

68.8%

SASA

68.6Å²

5PW

5a54 (CHAIN B)

31.2% EXPOSED

SASA atoms

5 / 16

% buried

68.8%

SASA

60.8Å²

5PW

5a54 (CHAIN D)

31.2% EXPOSED

SASA atoms

5 / 16

% buried

68.8%

SASA

71.8Å²

QS0

8c3g (CHAIN C)

31.2% EXPOSED

SASA atoms

10 / 32

% buried

68.8%

SASA

161.8Å²

QS0

8c3g (CHAIN D)

31.2% EXPOSED

SASA atoms

10 / 32

% buried

68.8%

SASA

144.9Å²

MLW

6t6a (CHAIN B)

31.2% EXPOSED

SASA atoms

5 / 16

% buried

68.8%

SASA

33.6Å²

EHB

3anq (CHAIN B)

31.2% EXPOSED

SASA atoms

5 / 16

% buried

68.8%

SASA

50.4Å²

JHW

6qu2 (CHAIN B)

30.4% EXPOSED

SASA atoms

7 / 23

% buried

69.6%

SASA

79.2Å²

KR8

6s1i (CHAIN B)

30.4% EXPOSED

SASA atoms

7 / 23

% buried

69.6%

SASA

44.7Å²

RUT

8c3q (CHAIN B)

30.2% EXPOSED

SASA atoms

13 / 43

% buried

69.8%

SASA

124.3Å²

RHW

7aj5 (CHAIN A)

29.4% EXPOSED

SASA atoms

5 / 17

% buried

70.6%

SASA

32.9Å²

QYZ

7a53 (CHAIN B)

29.4% EXPOSED

SASA atoms

5 / 17

% buried

70.6%

SASA

45.9Å²

QYZ

7a53 (CHAIN A)

29.4% EXPOSED

SASA atoms

5 / 17

% buried

70.6%

SASA

61.6Å²

QKG

6uwy (CHAIN C)

29.3% EXPOSED

SASA atoms

12 / 41

% buried

70.7%

SASA

63.4Å²

QKG

6uwy (CHAIN A)

29.3% EXPOSED

SASA atoms

12 / 41

% buried

70.7%

SASA

67.3Å²

QKG

6uwy (CHAIN B)

29.3% EXPOSED

SASA atoms

12 / 41

% buried

70.7%

SASA

60.2Å²

B6N

6eis (CHAIN C)

29.0% EXPOSED

SASA atoms

9 / 31

% buried

71.0%

SASA

72.7Å²

B7B

6eip (CHAIN D)

29.0% EXPOSED

SASA atoms

9 / 31

% buried

71.0%

SASA

104.1Å²

RK2

7aka (CHAIN A)

28.6% EXPOSED

SASA atoms

8 / 28

% buried

71.4%

SASA

38.5Å²

QZ2

7a55 (CHAIN B)

28.6% EXPOSED

SASA atoms

4 / 14

% buried

71.4%

SASA

34.4Å²

RKH

7ajs (CHAIN A)

27.8% EXPOSED

SASA atoms

5 / 18

% buried

72.2%

SASA

39.1Å²

4WD

7fht (CHAIN A)

27.8% EXPOSED

SASA atoms

5 / 18

% buried

72.2%

SASA

58.1Å²

RK8

7ake (CHAIN B)

27.6% EXPOSED

SASA atoms

8 / 29

% buried

72.4%

SASA

58.4Å²

7QQ

5a4e (CHAIN D)

26.7% EXPOSED

SASA atoms

4 / 15

% buried

73.3%

SASA

34.7Å²

QYW

7a5d (CHAIN A)

26.3% EXPOSED

SASA atoms

5 / 19

% buried

73.7%

SASA

43.7Å²

4H5

4yu2 (CHAIN A)

26.3% EXPOSED

SASA atoms

5 / 19

% buried

73.7%

SASA

43.5Å²

4H5

4yu2 (CHAIN D)

26.3% EXPOSED

SASA atoms

5 / 19

% buried

73.7%

SASA

47.9Å²

RK5

7akl (CHAIN A)

26.3% EXPOSED

SASA atoms

5 / 19

% buried

73.7%

SASA

46.4Å²

4H5

4yu2 (CHAIN B)

26.3% EXPOSED

SASA atoms

5 / 19

% buried

73.7%

SASA

39.8Å²

3RA

4aze (CHAIN C)

26.1% EXPOSED

SASA atoms

6 / 23

% buried

73.9%

SASA

45.5Å²

KR8

6s1i (CHAIN C)

26.1% EXPOSED

SASA atoms

6 / 23

% buried

73.9%

SASA

43.5Å²

3RA

4aze (CHAIN B)

26.1% EXPOSED

SASA atoms

6 / 23

% buried

73.9%

SASA

51.2Å²

RHH

7ak2 (CHAIN A)

25.9% EXPOSED

SASA atoms

7 / 27

% buried

74.1%

SASA

50.5Å²

KRQ

6s1b (CHAIN A)

25.9% EXPOSED

SASA atoms

7 / 27

% buried

74.1%

SASA

36.9Å²

B6N

6eis (CHAIN D)

25.8% EXPOSED

SASA atoms

8 / 31

% buried

74.2%

SASA

50.2Å²

B6N

6eis (CHAIN A)

25.8% EXPOSED

SASA atoms

8 / 31

% buried

74.2%

SASA

63.1Å²

RUT

8c3q (CHAIN A)

25.6% EXPOSED

SASA atoms

11 / 43

% buried

74.4%

SASA

112.8Å²

RHZ

7aj4 (CHAIN A)

25.0% EXPOSED

SASA atoms

4 / 16

% buried

75.0%

SASA

40.1Å²

RKZ

7ajy (CHAIN A)

25.0% EXPOSED

SASA atoms

7 / 28

% buried

75.0%

SASA

48.3Å²

RK8

7ake (CHAIN A)

24.1% EXPOSED

SASA atoms

7 / 29

% buried

75.9%

SASA

59.0Å²

KQK

6s17 (CHAIN A)

23.3% EXPOSED

SASA atoms

7 / 30

% buried

76.7%

SASA

38.5Å²

B7B

6eip (CHAIN A)

22.6% EXPOSED

SASA atoms

7 / 31

% buried

77.4%

SASA

107.7Å²

B6N

6eis (CHAIN B)

22.6% EXPOSED

SASA atoms

7 / 31

% buried

77.4%

SASA

48.5Å²

KQZ

6s1h (CHAIN A)

22.6% EXPOSED

SASA atoms

7 / 31

% buried

77.4%

SASA

37.1Å²

EKU

6ln1 (CHAIN B)

22.2% EXPOSED

SASA atoms

6 / 27

% buried

77.8%

SASA

31.4Å²

RHT

7aj7 (CHAIN A)

22.2% EXPOSED

SASA atoms

4 / 18

% buried

77.8%

SASA

39.1Å²

ZC3

5a4l (CHAIN B)

21.4% EXPOSED

SASA atoms

3 / 14

% buried

78.6%

SASA

44.0Å²

KRK

6s1j (CHAIN A)

20.6% EXPOSED

SASA atoms

7 / 34

% buried

79.4%

SASA

50.1Å²

KQW

6s14 (CHAIN A)

17.6% EXPOSED

SASA atoms

6 / 34

% buried

82.4%

SASA

44.2Å²

A00

9cy5 (CHAIN B)

0.0% EXPOSED

SASA atoms

0 / 0

% buried

100.0%

SASA

0.0Å²

A02

9ft2 (CHAIN A)

0.0% EXPOSED

SASA atoms

0 / 0

% buried

100.0%

SASA

0.0Å²

A03

9ft3 (CHAIN A)

0.0% EXPOSED

SASA atoms

0 / 0

% buried

100.0%

SASA

0.0Å²

A00

9cy5 (CHAIN A)

0.0% EXPOSED

SASA atoms

0 / 0

% buried

100.0%

SASA

0.0Å²

A04

9ft4 (CHAIN A)

0.0% EXPOSED

SASA atoms

0 / 0

% buried

100.0%

SASA

0.0Å²

A05

9ft6 (CHAIN A)

0.0% EXPOSED

SASA atoms

0 / 0

% buried

100.0%

SASA

0.0Å²

A01

9fuf (CHAIN A)

0.0% EXPOSED

SASA atoms

0 / 0

% buried

100.0%

SASA

0.0Å²

2D LIGAND MAP

GREEN (15–24 Å²)

YELLOW (24–34 Å²)

RED (≥34 Å²)

Atoms w/ SASA below 15 Å² are not highlighted

Highlighted atoms show linkable attachment sites

CHEMICAL PROPERTIES

QED: —

poor moderate good

Drug-likeness filters

Drug-likeness heuristics (informative, not absolute)