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WARHEAD COMMAND CENTER: 270a72a6 · Pi3K

K47

6mum (CHAIN A)

62.5% EXPOSED

SASA atoms

20 / 32

% buried

37.5%

SASA

183.1Å²

K47

6mum (CHAIN B)

59.4% EXPOSED

SASA atoms

19 / 32

% buried

40.6%

SASA

179.4Å²

K4A

6mul (CHAIN A)

50.0% EXPOSED

SASA atoms

17 / 34

% buried

50.0%

SASA

121.0Å²

NQ5

6tns (CHAIN A)

45.9% EXPOSED

SASA atoms

17 / 37

% buried

54.1%

SASA

158.5Å²

40L

4xe0 (CHAIN A)

45.2% EXPOSED

SASA atoms

14 / 31

% buried

54.8%

SASA

89.2Å²

K4A

6mul (CHAIN B)

44.1% EXPOSED

SASA atoms

15 / 34

% buried

55.9%

SASA

120.6Å²

NQ2

6tnr (CHAIN A)

42.9% EXPOSED

SASA atoms

15 / 35

% buried

57.1%

SASA

162.0Å²

HKN

6q74 (CHAIN A)

41.9% EXPOSED

SASA atoms

13 / 31

% buried

58.1%

SASA

89.1Å²

9NQ

5o83 (CHAIN A)

40.6% EXPOSED

SASA atoms

13 / 32

% buried

59.4%

SASA

102.0Å²

QDE

6zac (CHAIN A)

37.0% EXPOSED

SASA atoms

10 / 27

% buried

63.0%

SASA

86.3Å²

QDW

6zad (CHAIN A)

37.0% EXPOSED

SASA atoms

10 / 27

% buried

63.0%

SASA

73.1Å²

QD2

6zaa (CHAIN A)

36.4% EXPOSED

SASA atoms

12 / 33

% buried

63.6%

SASA

118.3Å²

HKQ

6q6y (CHAIN A)

34.8% EXPOSED

SASA atoms

8 / 23

% buried

65.2%

SASA

51.4Å²

SD5

7r26 (CHAIN A)

34.5% EXPOSED

SASA atoms

10 / 29

% buried

65.5%

SASA

85.8Å²

GFJ

6dgt (CHAIN A)

34.3% EXPOSED

SASA atoms

12 / 35

% buried

65.7%

SASA

99.6Å²

HKK

6q73 (CHAIN A)

27.8% EXPOSED

SASA atoms

5 / 18

% buried

72.2%

SASA

44.5Å²

2D LIGAND MAP

GREEN (15–24 Å²)

YELLOW (24–34 Å²)

RED (≥34 Å²)

Atoms w/ SASA below 15 Å² are not highlighted

Highlighted atoms show linkable attachment sites

CHEMICAL PROPERTIES

QED: —

poor moderate good

Drug-likeness filters

Drug-likeness heuristics (informative, not absolute)